Sugar acids and derivatives
Medchemexpress LLC Semaglutide-FITC (semaglutide-Lys(FITC)) | 4502.96 | 25 MG
Semaglutide-FITC is a FITC-labeled semaglutide, a GLP-1R agonist. It is used to directly track the distribution, cellular uptake, and transmembrane transport processes of vesicles. It can also be employed to study the movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
- FITC-labeled semaglutide (a GLP-1R agonist).
- Directly track the distribution, cellular uptake, and transmembrane transport process of vesicles via fluorescence imaging and flow cytometry.
- Study movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
Medchemexpress LLC Cdk1/Cyc B-IN-1 | 2459916-56-2 | 98.5% | 353.85 | 50 MG
CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. It triggers apoptosis and G2/M cell cycle arrest and demonstrates broad-spectrum cytotoxic action against cancer cell lines. In vitro, it is soluble in DMSO at 100 mg/mL.
- Induces apoptosis and G2/M cell cycle arrest
- Exhibits cytotoxic activity against HCT-116 cells (IC50 of 5.33 ± 0.69 μM)
- Exhibits cytotoxic activity against WI-38 cells (IC50 of 21.69 ± 1.04 μM)
- Shows antiproliferative activity against various human cancer cell lines
Medchemexpress LLC 4-Methylumbelliferyl 10mM 1mL
4-Methylumbelliferyl octanoate is a octoate 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase[1]
Medchemexpress LLC Integrin alpha V beta 5 protein | >95.0% | 20UG
Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant human integrin αVβ5 dimer expressed in HEK293 cells and supplied biotinylated with C-Avi and C-His tags. It is provided in microgram quantities and intended for receptor-ligand interaction studies, biochemical assays, and biophysical analyses that require the native extracellular domains.
- Biotinylated C-Avi and C-terminal His tags for detection and capture
- Expressed in HEK293 cells to preserve mammalian post-translational modifications
- High purity >95% as determined by reducing SDS-PAGE
- Molecular weight range 85-140 kDa consistent with heterodimeric extracellular domains
- Available in multiple microgram sizes to suit different assay scales
Medchemexpress LLC Perindopril acyl-β-D-glucuronide | 120398-66-5 | 544.59 | 1 MG
Perindopril acyl-β-D-glucuronide is a metabolite of Perindopril, which is an ACE inhibitor. This product is intended for research purposes only.
- For research use only.
- Not for sale to patients.
Medchemexpress LLC Integrin alpha V bet 100ug | 100ug
Integrin alpha V beta 6 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His C-Avi labeled tag Integrin alpha V beta 6 Protein Human (HEK293 His-Avi) has molecular weight of 90-150 kDa
Apexbio Technology LLC Cytochalasin D 22144-77-0 10mg
Cytochalasin D is a selective inhibitor of actin polymerization with a reported IC50 value of approximately 25 nM It exerts its biological effect by disrupting the formation and stability of actin filaments thereby influencing cellular processes dependent on cytoskeletal organization Through this mechanistic action Cytochalasin D induces cell cycle arrest at the G1-S transition via activation of p53-related signaling pathways In neuronal studies treatment with Cytochalasin D interferes with filopodial and lamellipodial dynamics by limiting protrusion elongation Additionally in vitro investigations demonstrated its utility in the study of virus-host interactions where blockade of actin polymerization inhibits pathogen entry and replication making Cytochalasin D a relevant reagent in cellular biology and virology research
Medchemexpress LLC Integrin alpha V beta 3 protein, mouse (HEK293, His) | >95.0% | 50UG
Integrin alpha V beta 3 protein, mouse (HEK293, His) is a recombinant heterodimeric integrin complex produced in HEK293 cells and supplied with a C-terminal His tag. It is intended for research use to support studies of integrin-mediated cell adhesion, signaling, and ligand interactions.
- Recombinant heterodimeric integrin complex (ITGAV:ITGB3).
- Expressed in HEK293 mammalian cells.
- C-terminal His tag for detection and purification.
- Purity greater than 95% as determined by reducing Tris-Bis PAGE.
- Observed molecular weight 90-130 kDa.
- Available in small-scale sizes suitable for biochemical assays (20 μg, 50 μg, 100 μg).
- For research use only; not for therapeutic or diagnostic use.
![Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286978.png-250.jpg)
Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG
CDK1/Cyc B-IN-1 is a small-molecule inhibitor selective for the CDK1-cyclin B kinase complex. It inhibits CDK1-cyclin B activity (reported IC50 ≈97 nM) and induces G2/M cell-cycle arrest and apoptosis in cancer cell lines. The compound is supplied as a solid with high purity and is used in biochemical and cellular studies of cell-cycle regulation.
- Selective CDK1-cyclin B inhibitor with reported IC50 ≈97 nM.
- Induces G2/M cell-cycle arrest and apoptosis in cell lines.
- Suitable for biochemical kinase assays and cell-based studies.
- High supplied purity for reproducible results.
- Soluble in DMSO at 100 mg/mL; use newly opened DMSO.
- Stable as a powder under recommended cold storage conditions.
Medchemexpress LLC (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide | 1147883-03-1 | 99.3% | 265.30 g/mol | C14H19NO4 | 25MG
EPI-589 is a redox-active small-molecule neuroprotective compound used in research on oxidative stress and neurodegenerative disorders. Supplied as a light yellow powder, it is formulated for both in vitro and in vivo experimentation and is readily soluble in DMSO with recommended vehicle formulations for animal dosing. The compound is characterized and shelf-stable under appropriate storage conditions.
- High purity: 99.3%.
- Chemical formula: C14H19NO4.
- Molecular weight: 265.30 g/mol.
- Form: solid powder, light yellow to yellow.
- In vitro solubility: DMSO 100 mg/mL.
- Recommended in vivo vehicles and clear solution ≥ 2.5 mg/mL.
- Storage: powder at -20°C (long term) or 4°C (short term).
Medchemexpress LLC Aurachin D | 108354-13-8 | 10 MG
Aurachin D is an antibiotic that inhibits Gram-positive bacteria and some fungi. It blocks NADH oxidation in beef heart submitochondrial particles.
- Acts as an antibiotic
- Inhibits Gram-positive bacteria
- Inhibits some fungi
- Blocks NADH oxidation
